For early prevention or inhibition of postmenopausal and age-related bone loss, nutritional interventions might be a first choice.
For some vitamins and minerals an important role in bone metabolism is known or suggested. Calcium and vitamin D support bone mineral density and are basic components in most preventive strategies. Magnesium is involved in a number of activities supporting bone strength, preservation, and remodeling.
Fluorine and strontium have bone-forming effects. However, high amounts of both elements may reduce bone strength.
Boron is especially effective in case of vitamin D, magnesium, and potassium deficiency.
Vitamin K is essential for the activation of osteocalcin.
Vitamin C is an important stimulus for osteoblast-derived proteins. Increasing the recommended amounts (US RDA 1989), adequate intakes (US DRI 1997), or assumed normal intakes of mentioned food components may lead to a considerable reduction or even prevention of bone loss, especially in late postmenopausal women and the elderly.
Ann Nutr Metab. 2006;50(2):85-94. Epub 2005 Dec 21.
Immune-enhancing role of vitamin C and zinc and effect on clinical conditions.
Wintergerst ES1, Maggini S, Hornig DH.