L'Efficacité de la supplémentation en cas d'ostéoporose

Des études cliniques ont démontré l'efficacité de la supplémentation du calcium, cuivre, manganèse et zinc pour la densité minérale osseuse de la colonne vertébrale chez la femme ménopausée. Chacune de ces études ont démontré l’importance des oligo-éléments pour le développement optimal de la matrice osseuse et du maintien de la densité osseuse.

​Abstract
Osteoporosis is a multifactorial disease with dimensions of genetics, endocrine function, exercise and nutritional considerations. Of particular considerations are calcium (Ca) status, Vitamin D, fluoride, magnesium and other trace elements.
Several trace elements, particularly copper (Cu), manganese (Mn) and zinc (Zn), are essential in bone metabolism as cofactors for specific enzymes. Our investigations regarding the role of Cu, Mn and Zn in bone metabolism include data from studies with animals on Cu- and Mn-deficient diets.
We have also demonstrated cellular deficiencies using bone powder implants, as well as fundamental changes in organic matrix constituents.
In clinical studies we have demonstrated the efficacy of Ca, Cu, Mn and Zn supplementation on spinal bone mineral density in postmenopausal women.
Each of these studies demonstrated the necessity of trace elements for optimal bone matrix development and bone density sustenance.

REFERENCE: 
http://www.ncbi.nlm.nih.gov/pubmed/8409100
J Am Coll Nutr. 1993 Aug;12(4):384-9.
The role of trace minerals in osteoporosis.
Saltman PD1, Strause LG.