Veuillez lire l'article complet (en anglais seulement) :
Geographic epidemiology of multiple sclerosis (MS) suggests that low vitamin D levels are a modifiable risk factor. Previous studies have shown that patients with MS have significantly lower vitamin D levels compared with healthy controls.
Vitamin D is a potent immunomodulator important for immune function and development, and it offers potential benefits by reducing inflammation.
Vitamin D has beneficial effects in experimental autoimmune encephalomyelitis, an animal model of MS.
In summation, these studies suggest that vitamin D may have therapeutic potential for MS.
This has not been established although preliminary clinical trials for vitamin D in MS look promising. Genetic studies suggest that genes associated with vitamin D are critical susceptible genes for MS. In this review, we discuss current research investigating the association between vitamin D and MS and the issues that need to be resolved.