Increased free radical production overwhelms the natural antioxidants defense mechanisms, subjecting individuals to hyperoxidant stress and thus leading to osteoporosis. The results reveal that antioxidant defenses are markedly decreased in osteoporotic women and male patients. Therefore, it may be suggested that oxidative stress plays an important role in the pathophysiology of osteoporosis is associated with increased bone resorption and low bone mass in otherwise healthy women. The total mineral and vitamin intake required for bone health (calcium, magnesium, phosphorus & vitamin D) was below the recommended, among majority of the sample. REFERENCE:
Pak J Med Sci. 2015 Jul-Aug;31(4):970-4. doi: 10.12669/pjms.314.8433. Bone mineral density and diet of teachers of College of Home Economics at Lahore. Javed Z1, Imam SF2, Imam N3, Saba K4, Bukhari MH5. Deficiencies of several B vitamins have been associated with cognitive dysfunction in many observational studies. More recently, deficiencies of folate (B9) and cobalamine (B12) have been studied in relation to hyperhomocysteinemia as potential determinants of cognitive impairment, dementia, and Alzheimer's disease. REFERENCE:
Brain Res Bull. 2006 Mar 15;69(1):1-19. Epub 2005 Nov 21. Nutritional factors, cognitive decline, and dementia.Del Parigi A1, Panza F, Capurso C, Solfrizzi V. Author information Abstract Nutritional factors and nutritional deficiencies have been repeatedly associated with cognitive impairment. Most of the evidence is based on cross-sectional studies, which cannot prove whether a nutritional deficit is the cause or the consequence of an impaired cognitive status. In fact, cognitive impairment, in turn, can determine changes in dietary habits and consequent nutritional deficiencies. We reviewed clinical and epidemiological studies from January 1983 to June 2004. Several cross-sectional and fewer prospective studies reported an association between dietary or supplemental intake of antioxidants and protection from cognitive decline and dementia. There are negative reports as well and some methodological biases might have affected the consistencies across studies. Deficiencies of several B vitamins have been associated with cognitive dysfunction in many observational studies. More recently, deficiencies of folate (B9) and cobalamine (B12) have been studied in relation to hyperhomocysteinemia as potential determinants of cognitive impairment, dementia, and Alzheimer's disease (AD). A small number of studies assessed the association between intake of macronutrients and cognitive function or dementia. Among the others, the intake of fatty acids and cholesterol has received particular attention. Although the results are not always consistent, most studies have reported a protective role of dietary intakes of poly- and mono-unsaturated fatty acids against cognitive decline and AD. We point out that well designed intervention studies are warranted in order to establish specific levels of micro- and macronutrient deficiencies and to set general recommendations for the population. |
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Août 2017
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